Recurrent Rhesus alloimmunization with early-onset severe fetal anaemia in a low-resource setting: a case report.

Authors

Willis Okumu Ochieng, Rosa Ndiema Chemwey, Elijah Kagondu Thagana

Published in

The Pan African medical journal. Volume 53. Pages 167. Epub Apr 20, 2026.

Abstract

Fetal anaemia due to Rhesus alloimmunization remains a significant cause of perinatal mortality and morbidity in low- and middle-income countries (LMICs), where the unaffordability of anti-D immunoglobulin compromises the care of Rhesus-negative women. We report a case of a 37-year-old multiparous RhD-negative woman who presented at 18+2 weeks of gestation with a history of recurrent fetal losses attributed to recurrent Rhesus alloimmunization. Serial fetal cerebral blood flow assessments demonstrated progressively worsening anaemia, prompting two intrauterine transfusions. Despite intervention, intrauterine fetal demise still occurred. This case highlights the aggressive course of recurrent Rhesus alloimmunization and the challenges of management in a low-resource setting.

PMID:
42604227
Bibliographic data and abstract were imported from PubMed on 16 Aug 2026.

Read full publication at:
Please sign in to see all details.

Stats

1-terrible, 9-excellent. How would you rate this publication? Sign in in to submit your rating.

Post a comment

You need to be signed in to post comments. You can sign in here.

Comments

There are no comments yet.