Development of a Cu₂O@AlOOH nanocatalyst for sustainable synthesis of acetanilides and 4-aryl-NH-1,2,3-triazoles with enhanced catalytic activity.

Authors

Neeraj Kumari, Shashikant Tiwari, Diwan S Rawat, Manish Rawat

Published in

Dalton transactions (Cambridge, England : 2003). Aug 17, 2026. Epub Aug 17, 2026.

Abstract

Designing heterogeneous catalysts utilizing abundantly available transition metal-based nanoparticles has attracted significant interest in the area of research for the sustainable and efficient synthesis of N-heterocyclic frameworks due to their convenient separation, recyclability, and low metal leaching. In this work, we reported the novel synthesis of a Cu₂O@AlOOH nanocatalyst (E factor 4.88) for the preparation of acetanilides using aniline and acetic acid under solvent-free conditions. Furthermore, the as-prepared nanocatalyst was used for the synthesis of 4-aryl-NH-1,2,3-triazoles from benzaldehyde, nitromethane, and sodium azide. The as-prepared catalyst was well characterized by scanning electron microscopy, transmission electron microscopy, powder X-ray diffraction, the Brunauer-Emmett-Teller technique, and X-ray photoelectron spectroscopy. The developed protocol demonstrates various advantages such as excellent yield of the product in a short period of time, green solvent, environmentally benign reaction conditions, broad substrate applicability, better green chemistry metrics such as low E-factor, high atom economy, high reaction mass efficiency, high turnover number and good recyclability up to five runs without significant loss in its catalytic activity.

PMID:
42605612
Bibliographic data and abstract were imported from PubMed on 17 Aug 2026.

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