Authors
Esther Ugo Alum, Bashar Haruna Gulumbe, Friday Ogbu Edeh, Christine Ainebyoona, Daniel Ejim Uti, Okechukwu Paul-Chima Ugwu, Benedict Nnachi Alum, Michael Ben Okon, Patrick Maduabuchi Aja, Vaithiyalingam Subramanian Manjula, Peter Chinedu Agu
Published in
Expert review of anti-infective therapy. Aug 17, 2026. Epub Aug 17, 2026.
Abstract
Antimicrobial resistance (AMR) is a major health-system challenge in Uganda. Western Uganda has documented inappropriate antibiotic prescribing and local resistance patterns, but evidence on routine antimicrobial stewardship (AMS) implementation remains fragmented.
This structured narrative policy and implementation review synthesizes evidence on AMR and antimicrobial stewardship (AMS) implementation in Western Uganda, drawing on Western Uganda-specific studies, Uganda-wide evidence, national policy documents, and broader low- and middle-income country implementation literature. Evidence was identified through targeted PubMed searches, World Health Organization resources, and Ugandan Ministry of Health repositories focused on AMR, AMS, antibiotic use, diagnostics, surveillance, community pharmacies, drug shops, One Health, and low-resource settings.
The strongest immediate case for stewardship in Western Uganda is supported by local prescribing studies, national hospital point-prevalence data, and Uganda's current policy framework. A feasible minimum package should combine named facility responsibility, Uganda Clinical Guideline and AWaRe-informed prescribing support, small-sample prescription review, laboratory referral and feedback, private pharmacy engagement, and district supervision. The phased framework proposed in this review is an author-developed implementation synthesis; it has not yet been adopted or evaluated.
PMID:
42606019
Bibliographic data and abstract were imported from PubMed on 17 Aug 2026.
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