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Scandium and Lutetium Metallacyclopropanes: Synthesis, Bonding, and Sterically Driven Reactivity.

Created on 17 Aug 2026

Authors

Dajiang Huang, Tianyu Li, Miaomiao Zhu, Junnian Wei, Yulong Li, Wen-Xiong Zhang

Published in

Inorganic chemistry. Volume 65. Issue 32. Pages 18916-18924. Aug 17, 2026.

Abstract

As the class of the smallest metallacycles, transition-metal metallacyclopropanes have been widely studied, whereas scandium, yttrium, and lanthanide analogues have remained elusive. Herein, we report the first synthesis and characterization of scandium and lutetium metallacyclopropanes, 2-Sc and 2-Lu. Reactivity studies reveal a striking divergence: while 2-Sc is limited to redox processes, 2-Lu displays versatile insertion reactivity with various unsaturated substrates. DFT analysis indicates that the superior reactivity of 2-Lu is not driven by electronic nucleophilicity but rather by kinetic accessibility. The larger ionic radius and rare coordination mode of the Lu center provide a more open coordination sphere that outweighs electronic stabilization. This work highlights the important role of steric accessibility in controlling the divergent reactivity of highly strained Sc- and Lu-metallacyclopropane complexes.

PMID:
42606267
Bibliographic data and abstract were imported from PubMed on 17 Aug 2026.

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