Authors
Jichen Zhao, Xuewei Kan, Xin Tang, Xin Huang, Shuo Li, Shiyu Ji, Yimin Li, Xuyan Zhao, Yi Tan, Ting Si, Guiqiang Li, Chunyu Zhao, Jun Tang, Yu Zhang, Yuen Wu
Published in
Advanced materials (Deerfield Beach, Fla.). Pages e74636. Aug 17, 2026. Epub Aug 17, 2026.
Abstract
Wearable bioelectronics are dominated by low-power sensing, whereas effective therapy requires sustained molecular fluxes that conventional soft devices rarely support. A central challenge is simultaneously maintaining solid-solid charge transport, hydration-dependent ionic conduction, and biofluid resistance within a lightweight, fixture-free architecture. Here, we report a vapor-fed electrochemical materials architecture for skin-conformal oxygen delivery. The system integrates a mechanically interlocking 3D current collector/catalyst interface to stabilize electronic transport, femtosecond-laser-defined microchannels to reconstruct vapor-phase mass transport within an all-solid-state membrane electrode assembly, and a phase-selective porous barrier blocking exudate intrusion while preserving gas diffusion. This hierarchical design enables an ultralight (<4 g) patch to operate at high current densities (>100 mA cm-2), sustaining continuous operation for 735 h to deliver 16.8 L of high-purity (>99%) O2. The architecture remains stable for >500 h in simulated exudates and supports efficient transdermal oxygen transport across porcine skin. In a rat pressure-ulcer model, short-course treatment accelerates early wound closure 1.7-fold at day 3, enhancing M2 macrophage polarization and vascular normalization. These results establish a materials framework for translating wearable bioelectronics from passive information interfaces to active molecular-delivery systems.
PMID:
42606160
Bibliographic data and abstract were imported from PubMed on 17 Aug 2026.
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