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Horizontal transfer of QAC resistance genes between Listeria innocua and Listeria monocytogenes strains isolated from a food production environment.

Created on 18 Aug 2026

Authors

Yarlenis Coello-Delgado, Adrián Gómez Baltazar, Mauricio Redondo-Solano, Angélica Godínez Oviedo, Juan Ramiro Pacheco Aguilar, Montserrat Hernández Iturriaga

Published in

Canadian journal of microbiology. Volume 72. Pages 1-9. Jan 01, 2026.

Abstract

The objective of this study was to determine the presence of quaternary ammonium compound (QAC) resistance genes in Listeria spp. strains and to evaluate the effect of temperature and substrate on interspecies gene transfer. A total of 23 L. monocytogenes strains, four L. innocua and 37 Listeria spp. isolates (excluding L. grayi, L. ivanovii, L. seeligeri, and L. welshimeri) were recovered from surfaces in a frozen vegetable processing facility. The presence of the bcrABC gene was assessed by endpoint PCR. The bcrABC gene was detected in 73.91% (17/23) of L. monocytogenes isolates, in 50.00% (2/4) of L. innocua strains and was not detected in the other Listeria species (0/37). Two L. innocua strains carrying the bcrABC gene and two L. monocytogenes strains lacking it were selected for mixed culture experiments. Four co-cultures were prepared, inoculated into tryptic soy broth and spinach extract, and incubated at 4, 25, and 36 °C for 10 days. Horizontal transfer of the bcrABC gene was observed in 7.87% (17/216) of reactions in tryptic soy broth and spinach extract, with higher frequencies at 25 °C (10/216, 4.63%) and 36 °C (6/216, 2.78%) and lower frequencies at 4 °C (1/216, 0.46%). Recipient L. monocytogenes strains revealed increased resistance to QACs (500 μg/mL).

PMID:
42606832
Bibliographic data and abstract were imported from PubMed on 18 Aug 2026.

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