Severe Checkpoint Inhibitor Pneumonitis and Lung Cancer Recurrence After Carbon-ion Radiotherapy in a Patient with Lung Squamous Cell Carcinoma.

Authors

Chenran Xu, Yiting Zheng, Yi Wei, Qian Jin

Published in

Practical radiation oncology. Aug 17, 2026. Epub Aug 17, 2026.

Abstract

Carbon-ion radiotherapy (CIRT) holds promise for central lung cancer owing to its non-invasiveness and precision. We report a case of lung squamous cell carcinoma treated with neoadjuvant chemoimmunotherapy followed by CIRT. The course was complicated by severe checkpoint inhibitor pneumonitis with concurrent Pneumocystis jirovecii pneumonia and subsequent recurrence, highlighting the challenge of managing multimodality toxicities during aggressive local control.

PMID:
42607753
Bibliographic data and abstract were imported from PubMed on 18 Aug 2026.

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