Authors
Shuanjun Zhang, Juxian Zhao, Fang Yang, Cuiwen Li, Haixia Wei, Wen Li, Zhonghua Bai, Huiwen Wang
Published in
Frontiers in medicine. Volume 13. Pages 1839041. Epub Aug 03, 2026.
Abstract
For parturients with contraindications to neuraxial anesthesia, GA remains the primary alternative. However, conventional opioid-based GA may increase the risk of adverse neonatal outcomes. Therefore, exploring opioid-sparing GA combined with bilateral QLB is of considerable clinical value for reducing potential maternal and neonatal risks.In the present case, the patient was a 35-year-old full-term parturient with spinal deformity who declined neuraxial anesthesia, constituting a contraindication to such techniques.During cesarean delivery, we successfully implemented an opioid-sparing GA regimen combined with bilateral QLB. The essential components of GA-hypnosis, analgesia, muscle relaxation, and attenuation of the stress response-were achieved through a multimodal approach. The anesthetic management was carefully designed following a comprehensive preoperative evaluation and a thorough analysis of the challenges associated with conventional opioid-based GA in this patient. Multidisciplinary collaboration and meticulous perioperative planning were emphasized throughout the peripartum period. This anesthetic approach effectively integrated the advantages of regional nerve block and GA. Notably, the neonate exhibited no signs of opioid-related respiratory depression, with no occurrence of low Apgar scores, and no resuscitative interventions were required after delivery. This case highlights a novel opioid-sparing strategy for cesarean delivery under GA.
PMID:
42609362
Bibliographic data and abstract were imported from PubMed on 18 Aug 2026.
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