Large Deep Temporal Lipomatous Mass Mimicking Liposarcoma on MRI: A Brief Clinical Report.

Authors

Woosang Jeon, Chang Hun Oh, Minseob Eom, Jiye Kim, Sug Won Kim

Published in

The Journal of craniofacial surgery. Aug 18, 2026. Epub Aug 18, 2026.

Abstract

Intramuscular lipoma of the temporalis muscle is rare and may be difficult to distinguish from malignant lipomatous tumors when MRI shows atypical features. A 76-year-old woman presented with a progressively enlarging right temporal mass and a history of prior subcutaneous lipoma excision at the same site. Contrast-enhanced MRI revealed a large deep lipomatous mass with a heterogeneous nonadipose component involving the anterior temporalis muscle, raising concern for atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDL). The lesion was excised through a preauricular-based incision with temporal extension. Intraoperative frozen section suggested a benign lipomatous lesion, and final pathology confirmed intramuscular lipoma without lipoblasts or nuclear atypia. MDM2 immunostaining was negative, whereas CDK4 showed only focal nuclear staining. At 6 months, facial nerve function was preserved, and no clinical recurrence was evident. This case highlights that a large deep temporal intramuscular lipoma may mimic liposarcoma on MRI and that safe management requires integrated radiologic, intraoperative, and histopathologic correlation.

PMID:
42610576
Bibliographic data and abstract were imported from PubMed on 18 Aug 2026.

Read full publication at:
Please sign in to see all details.

Stats

1-terrible, 9-excellent. How would you rate this publication? Sign in in to submit your rating.

Post a comment

You need to be signed in to post comments. You can sign in here.

Comments

There are no comments yet.