Effectiveness of Therapeutic Sport Footwear in Prevention of Ulcer Recurrence in Persons with Diabetic Foot Disease.

Authors

Michela Di Venanzio, Ermanno Bellizzi, Marco Meloni, Federico Rolando Bonanni, Laura Giurato, Daniele Morosetti, Aikaterini Andreadi, Alfonso Bellia, Davide Lauro

Published in

The international journal of lower extremity wounds. Pages 15347346261479522. Aug 18, 2026. Epub Aug 18, 2026.

Abstract

Recurrence of diabetic foot ulcer (DFU) remains a major clinical challenge in patients with diabetes. Therapeutic footwear is a cornerstone of secondary prevention as it reduces plantar pressure and mechanical stress. However, most available evidence focuses on traditional orthopedic footwear, while prospective data on therapeutic sport footwear designed for daily physical activities are poor. This study aimed to evaluate the effectiveness of therapeutic sport footwear with a semi-rigid biomechanical sole (termed YDA) with combined insole in preventing ulcer recurrence in patients with diabetes at high risk of re-ulceration. The study was a single-arm, uncontrolled, retrospective observational study including consecutive patients with diabetes and a history of DFU referred to a tertiary diabetic foot center between January 2024 and March 2025. All included patients wore YDA as therapeutic footwear during the study period. In addition, they were managed through a multidisciplinary protocol including regular clinical follow-up, risk-factor monitoring, and structured patient education. The 1-year outcomes included: ulcer recurrence, minor and major amputations. Overall, 47 patients were included (68.1% male; mean age 68.3 ± 8.4 years). Peripheral neuropathy was present in all patients and peripheral arterial disease in 55.3%. At 1 year of follow-up, ulcer recurrence occurred in 14.9% of patients, minor amputation in 6.4%, and no major amputations were recorded. The multivariate analysis showed that discontinuous use of therapeutic footwear was strongly associated with ulcer recurrence (OR 8.9, 95% CI 2.1-37.5; p < 0.0001) and minor amputation (OR 10.5, 95% CI 2.0-55; p = 0.004). Peripheral arterial disease was independently associated with minor amputation (OR 5.2, 95% CI 1.3-20.6; p = 0.02). The use of specific sport footwear with a semi-rigid biomechanical sole resulted in a low rate of re-ulceration.

PMID:
42610825
Bibliographic data and abstract were imported from PubMed on 18 Aug 2026.

Read full publication at:
Please sign in to see all details.

Stats

1-terrible, 9-excellent. How would you rate this publication? Sign in in to submit your rating.

Post a comment

You need to be signed in to post comments. You can sign in here.

Comments

There are no comments yet.