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Follicular Lymphoma Involving the Supraglottic Larynx in a Patient with Recurrent Cutaneous B-cell Lymphoproliferative Lesions: A Case Report.

Created on 20 Aug 2026

Authors

Ryohei Asai, Hiroumi Matsuzaki, Shimon Otake, Tang Xiaoyan, Takeshi Oshima

Published in

Internal medicine (Tokyo, Japan). Aug 19, 2026. Epub Aug 19, 2026.

Abstract

We report a rare case of follicular lymphoma involving the supraglottic larynx in an elderly woman with progressive hoarseness and potential airway compromise. Microlaryngoscopic resection was performed before systemic staging. Histopathology showed grade 1-2 follicular lymphoma. Postoperative FDG PET/CT and a bone marrow biopsy revealed no nodal, visceral, or bone marrow involvement at diagnosis. Because the clonal relationship with previous cutaneous B-cell lymphoproliferative lesions could not be assessed, a primary laryngeal origin could not be established. Involved-site radiotherapy was proposed, but declined by the patient. The patient remained free of local recurrence 6 months after surgery.

PMID:
42618266
Bibliographic data and abstract were imported from PubMed on 20 Aug 2026.

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