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In Regulatory First, Myeloma Drug Approved Based on MRD Negativity.

Created on 21 Aug 2026

Published in

Cancer discovery. Pages OF1. Aug 21, 2026. Epub Aug 21, 2026.

Abstract

The FDA has approved iberdomide for multiple myeloma based on minimal residual disease negativity, marking a first for the disease. The drug also ushers in a new generation of targeted protein degraders, with several more potent cereblon E3 ligase modulators already in clinical development.

PMID:
42627098
Bibliographic data and abstract were imported from PubMed on 21 Aug 2026.

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