Patterns of Bacterial Infection and Antibiotic Resistance in Canine Corneal Ulcers: A Retrospective Analysis (Berlin, Germany, 2021-2024).

Authors

Adriana Morales, Esmeralda Delgado, Hugo Vilhena, Ingrid Allgoewer

Published in

Veterinary ophthalmology. Volume 29. Issue 5. Pages e70253.

Abstract

To investigate the bacterial spectrum and antimicrobial susceptibility patterns of isolates obtained from canine corneal ulcers, assessing possible associations with breed, season, and multidrug resistance.
A retrospective review was conducted on corneal ulcers from 112 dogs between May 2021 and June 2024 at a specialized veterinary ophthalmology clinic in Berlin, Germany. Bacteriological cultures and antimicrobial susceptibility tests (ASTs) were analyzed according to the Clinical and Laboratory Standards Institute (CLSI).
Brachycephalic breeds represented 79.5% of affected dogs. Positive bacterial growth was obtained in 79.5% (89/112) of samples, yielding 107 isolates. Gram-positive organisms predominated (72.2%), mainly Staphylococcus pseudintermedius (27.8%) and β-hemolytic Streptococcus (19.4%). Among 100 isolates tested, 59% were resistant to penicillins, while 71% were susceptible to aminoglycosides and fluoroquinolones, 73% to amoxicillin-clavulanate, and 78% to tetracyclines. Multidrug resistance (MDR) occurred in 27% of isolates.
Staphylococcus pseudintermedius and β-hemolytic Streptococcus were the main bacterial agents associated with infected canine corneal ulcers. The relatively high frequency of MDR isolates emphasizes the need for culture-based therapy and ongoing regional surveillance to guide empirical antibiotic use.

PMID:
42627045
Bibliographic data and abstract were imported from PubMed on 21 Aug 2026.

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