A solitary lytic rib lesion mimicking primary Chest Wall malignancy as the initial presentation of multiple myeloma.

Authors

İsmail Tombul, Elgün Valiyev, Tuğçe A Akbal Ersöz, Mehmet Zengin

Published in

Oxford medical case reports. Volume 2026. Issue 8. Pages omag152. Epub Aug 22, 2026.

Abstract

Multiple myeloma is predominantly observed in the geriatric population and accounts for approximately 10% of all hematologic malignancies. It typically presents with multiple bone lesions and clinical features fulfilling the CRAB criteria (hyperCalcemia, Renal failure, Anemia, and Bone involvement). Herein, we present the case of an 82-year-old patient who presented with a solitary lytic rib lesion in the left hemithorax. The patient exhibited only bone pain among the CRAB features, and systemic radiological evaluation revealed no additional lesions. The initial clinical impression was that of a primary malignancy of the thoracic wall. A diagnosis of multiple myeloma was confirmed based on the histopathological evaluation of both the solitary lytic rib lesion and bone marrow samples.

PMID:
42633091
Bibliographic data and abstract were imported from PubMed on 23 Aug 2026.

Read full publication at:
Please sign in to see all details.

Stats

1-terrible, 9-excellent. How would you rate this publication? Sign in in to submit your rating.

Post a comment

You need to be signed in to post comments. You can sign in here.

Comments

There are no comments yet.