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Giant post-traumatic liponecrotic granuloma of the gluteal region: A case report with multimodality imaging findings.

Created on 23 Aug 2026

Authors

Chaimae Abourak, Yahya El Harras, Kaoutar Imrani, Ittimade Nassar, Yassine Hafiani

Published in

Radiology case reports. Volume 21. Issue 11. Pages 5362-5367. Epub Aug 13, 2026.

Abstract

Post-traumatic liponecrotic granuloma is a benign soft-tissue lesion resulting from adipose tissue necrosis after blunt trauma. Although post-traumatic fat necrosis is a recognized entity, large encapsulated lesions with a pseudotumoral appearance are rare and may closely mimic soft-tissue neoplasms, creating a diagnostic challenge. In this setting, multimodality imaging is essential for accurate lesion characterization and appropriate patient management. We report the case of a 40-year-old woman presenting with a progressively enlarging left gluteal mass that developed over 5 years following a road traffic accident. Clinical examination revealed a well-defined, firm, painless mass without overlying inflammatory skin changes. Ultrasound demonstrated a large avascular subcutaneous lesion measuring 122 × 109 × 89 mm (craniocaudal × anteroposterior × transverse). Computed tomography showed a well-circumscribed lobulated fat-containing mass with internal calcifications. Magnetic resonance imaging demonstrated a well-defined lobulated subcutaneous lesion with a thin hypointense capsule enclosing a central fatty component that was hyperintense on T1- and T2-weighted images, completely suppressed on fat-saturated sequences, and showed no significant postcontrast enhancement. The combination of a history of trauma and characteristic multimodality imaging findings strongly supported the presumptive diagnosis of post-traumatic liponecrotic granuloma. This case highlights the importance of correlating clinical history with ultrasound, computed tomography, and magnetic resonance imaging to accurately characterize chronic post-traumatic soft-tissue lesions. It also illustrates the diagnostic challenge posed by large encapsulated fat necrosis with a pseudotumoral appearance and emphasizes the value of multimodality imaging in establishing a confident presumptive diagnosis while potentially avoiding unnecessary invasive procedures.

PMID:
42633175
Bibliographic data and abstract were imported from PubMed on 23 Aug 2026.

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