Authors
Carina Oschlies, Barbara Riond, Christian Gerspach, Angelika Schoster
Published in
Journal of veterinary internal medicine. Volume 40. Issue 4. Jul 01, 2026.
Abstract
Ruminants with left-sided abomasal displacement (LDA) often develop metabolic alkalosis and paradoxical aciduria.
To descriptively characterize electrolytes and acid-base variables in cows with LDA compared to healthy cows using the physicochemical (Stewart) approach, and to exploratively assess the influence of blood and urinary electrolytes on pH.
Twenty healthy dairy cows and 20 cows with LDA.
Retrospective cross-sectional study. Electrolytes, pH, total protein (TP), β-hydroxybutyrate (BHB), and glucose were measured in venous blood and urine. Base excess, anion gap, strong ion difference (SID), and strong ion gap (SIG) were calculated. Associations were evaluated using 2 stepwise forward multiple linear regression models.
Cows with LDA had significantly lower venous concentrations of sodium, chloride, potassium, magnesium, and calcium (P = .0013, P = .0023, P < .001, P < .001, P < .001), higher BHB (P < .001), and higher blood pH (P = .003) compared to controls. Calculated SID3, SID4, SID5, and SIG did not differ significantly between groups (P = .2, P = .37, P = .40, P = .62). In urine, cows with LDA showed significantly lower concentrations of Na+, K+, Cl-, Mg2+, and HCO₃- (P = .0007, P < .001, P < .001, P = .004, P < .001). Urinary SID3 and SID5 were also significantly lower (both P < .001).
Acid-base disturbances in cows with LDA can be interpreted using the physicochemical approach. Alterations in electrolyte concentrations contribute to changes in pH.
PMID:
42636341
Bibliographic data and abstract were imported from PubMed on 25 Aug 2026.
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