In biliary atresia, cholangiography still remains the diagnostic gold standard.

Authors

Rani Kassir, Grégoire Schneider, Rémi Dubois, Guillaume Rossignol

Published in

Pediatric surgery international. Volume 42. Issue 1. Aug 24, 2026. Epub Aug 24, 2026.

Abstract

Early diagnosis of biliary atresia (BA) is essential to maximize the success of Kasai portoenterostomy. We read with interest the recent study reporting excellent diagnostic performance of abdominal ultrasonography combined with serum gamma-glutamyl transferase (GGT) for the diagnosis of BA. While these findings are encouraging, their applicability to younger infants deserves caution, as the study cohort was diagnosed relatively late. During the earliest stages of BA, ultrasonographic findings, serum GGT levels, and even liver biopsy may be less reliable, increasing the risk of delayed diagnosis. When BA remains clinically suspected, preserving the therapeutic window for Kasai portoenterostomy should take precedence, and cholangiography should remain the diagnostic gold standard rather than be delayed by repeated non-invasive investigations.

PMID:
42635813
Bibliographic data and abstract were imported from PubMed on 25 Aug 2026.

Read full publication at:
Please sign in to see all details.

Stats

1-terrible, 9-excellent. How would you rate this publication? Sign in in to submit your rating.

Post a comment

You need to be signed in to post comments. You can sign in here.

Comments

There are no comments yet.