Authors
Qinwen Deng, Kai Wu, Longhan Xie, Li Zhang, Huajun Wang, Xiaofei Zheng
Published in
Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery. Volume 40. Issue 8. Pages 1314-1319. Aug 15, 2026.
Abstract
To review the research progress and application prospects of brain-computer interface (BCI) in orthopedic rehabilitation and motor function restoration.
Through literature analysis, the neurophysiological mechanisms of BCI in improving central motor drive deficits, technical paradigms, and clinical evidence in quadriceps inhibition after anterior cruciate ligament reconstruction and other orthopedic conditions were summarized, and the challenges in clinical translation were discussed.
BCI decodes movement-related neural signals and establishes closed-loop feedback between central and peripheral systems, which can enhance corticospinal tract excitability, induce neuroplasticity, and alleviate postoperative muscle inhibition and dysfunction caused by insufficient central motor drive. Available evidence indicates that motor imagery-based BCI training can improve quadriceps voluntary activation rate and reduce muscle strength loss after surgery, showing potential intervention value in other orthopedic conditions.
BCI holds promise as an important adjunct to conventional orthopedic rehabilitation, particularly for patients with central motor drive deficits. However, its clinical translation still faces challenges including insufficient mechanistic evidence, high patient heterogeneity, and lack of standardized training protocols, which represent key directions for future research.
PMID:
42642203
Bibliographic data and abstract were imported from PubMed on 26 Aug 2026.
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