Weekend Warrior Physical Activity, Sedentary Behavior, and Incident Disability in Middle-Aged and Older Adults: A UK Biobank Accelerometer Study.

Authors

Xuan Zhu, Heyan Xia, Tao Sun, Xiaojun Wang

Published in

Geriatrics & gerontology international. Volume 26. Issue 9. Pages e70818.

Abstract

Regular moderate-to-vigorous physical activity (MVPA) is associated with lower risks of functional decline and disability. Whether concentrating MVPA into 1 or 2 days per week-the "weekend warrior" pattern-is associated with disability risk similarly to regularly distributed activity remains unclear, particularly among individuals with high sedentary behavior.
We analyzed wrist-worn accelerometer data from 41 225 UK Biobank participants without identifiable baseline disability based on available indicators (mean age 61.6 years; 60.3% women). Participants were classified as inactive (< 150 min/week), weekend warriors (≥ 150 min/week with ≥ 50% accumulated in 1-2 days), or regularly active (≥ 150 min/week but not weekend warriors). Disability was assessed once during follow-up and defined as a self-reported need for assistance with at least one of six activities of daily living because of a health condition. Associations with incident disability were estimated using Cox proportional hazards models for interval-censored outcomes, adjusting for sociodemographic characteristics, lifestyle factors, and baseline health status.
During a median follow-up of 7.7 years, 2589 participants were classified as having disability at follow-up. Compared with inactive individuals, weekend warrior and regularly active patterns were associated with similarly lower disability risk (weekend warrior: HR 0.68, 95% CI 0.61-0.75; regularly active: HR 0.66, 95% CI 0.60-0.73). These associations were observed across sedentary behavior levels.
Accumulating recommended MVPA within 1 or 2 days per week was associated with disability risk reductions comparable to regularly distributed activity. Flexible activity patterns may help support functional independence and healthy aging.

PMID:
42642715
Bibliographic data and abstract were imported from PubMed on 26 Aug 2026.

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