Collagenofibrotic glomerulopathy in 3 tortoises.

Authors

Hayato Hamano, Kenichi Watanabe, Manabu Yamada, Ginga Ohashi, Yoshiyasu Kobayashi

Published in

Veterinary pathology. Pages 3009858261480629. Aug 26, 2026. Epub Aug 26, 2026.

Abstract

Collagenofibrotic glomerulopathy (CG) is a rare renal disease characterized by the abnormal accumulation of type III collagen within glomeruli. This is the first study to report CG in 3 tortoises housed within the same facility. Histologic analyses revealed eosinophilic glomerular deposits, which had segmental positive immunolabeling with anti-type III collagen antibodies by immunohistochemistry. These deposits were observed in approximately 70% of glomeruli in case 1, 50% in case 2, and 95% in case 3. An ultrastructural examination confirmed that the deposits were comprised of irregularly arranged collagen fibrils with periodic transverse striations mixed with fibrils of a smaller diameter. Additionally, similar deposits were noted in the walls of arterioles in the spleen of case 3. Therefore, CG in tortoises may be a systemic disease.

PMID:
42648879
Bibliographic data and abstract were imported from PubMed on 27 Aug 2026.

Read full publication at:
Please sign in to see all details.

Stats

1-terrible, 9-excellent. How would you rate this publication? Sign in in to submit your rating.

Post a comment

You need to be signed in to post comments. You can sign in here.

Comments

There are no comments yet.