Nissen Fundoplication: 70 years of a simple and brilliant idea in the surgical treatment of gastroesophageal reflux disease.

Authors

Fernando Antonio Siqueira Pinheiro, Jean Claude Boulez, Nelson Adami Andreollo, Paulo Kassab

Published in

Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery. Volume 39. Pages e1955. Epub Aug 21, 2026.

Abstract

Rudolf Nissen published his first two cases in 1956, thus inaugurating the era of pathological gastroesophageal reflux surgery. From the 1970s onwards, with Nissen fundoplication increasingly used as the treatment of choice for gastroesophageal reflux and hiatal hernia, minor alterations were proposed. Nissen's greatest legacy: not just an operation, but a way of thinking about surgery as a restless, rigorous, and profoundly patient-centered procedure.

PMID:
42659517
Bibliographic data and abstract were imported from PubMed on 28 Aug 2026.

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