Authors
Hung-Yao Yun, Hsin-Wei Chou, Yi-Hsuan Su, Yu-Hsuan Chien
Published in
Neonatology. Pages 1. Aug 28, 2026. Epub Aug 28, 2026.
Abstract
Congenital portosystemic shunts (CPSS) are rare vascular anomalies that can lead to hyperammonemia and liver dysfunction.
A 1-month-old infant was diagnosed with incidental patent ductus venosus (PDV) and a focal nodular hyperplasia-like liver nodule. Laboratory tests revealed hyperammonemia (192 µmol/L) and cholestasis. Imaging confirmed a 7.8-mm shunt connecting the left portal vein to the inferior vena cava. Urgent transcatheter closure was performed via the right jugular vein using a 12/10-mm LifeTech™ Konar-MFO occluder. Post-procedural imaging showed complete shunt occlusion, and ammonia levels rapidly decreased to 71.8 µmol/L. Cholestasis improved, and the patient was discharged without complications.
This report describes the first global use of the Konar-MFO device for PDV closure. Transcatheter embolization using this device is a safe and effective minimally invasive treatment for symptomatic PDV in young infants.
PMID:
42664179
Bibliographic data and abstract were imported from PubMed on 29 Aug 2026.
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