Autophagy inhibition in pancreatic cancer: hope or hype?

Authors

Emma Guilbaud, Edna Cukierman, Igor Astsaturov, Lorenzo Galluzzi

Published in

Autophagy reports. Volume 5. Issue 1. Pages 2721748. Epub Aug 27, 2026.

Abstract

Autophagy promotes tumor progression and immune evasion by numerous mechanisms, representing a promising target for novel (immuno)therapeutic interventions in multiple oncological indications. An expanding literature, however, suggests that safely and effectively targeting autophagy in the clinic remains challenging, especially in populations as complex to manage as patients with pancreatic cancer.

PMID:
42666728
Bibliographic data and abstract were imported from PubMed on 29 Aug 2026.

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