Rapid-Onset Amoxicillin-Clavulanate Liver Injury Requires Stronger Exclusion of Alternative Causes and Fuller Causality Reporting in Atypical DILI Case Reports.

Authors

Muhammad Abdullah Awan, Hammad-Ud-Din Raza

Published in

Clinical case reports. Volume 14. Issue 9. Pages e73369. Epub Aug 28, 2026.

Abstract

Rapid-onset drug-induced liver injury after amoxicillin-clavulanate is clinically important, but atypical latency requires particularly careful exclusion of alternative causes. Future reports should provide complete exposure chronology, infectious and autoimmune exclusion, concomitant-drug assessment, RUCAM itemization, and longer biochemical follow-up before assigning strong causality to amoxicillin-clavulanate.

PMID:
42668824
Bibliographic data and abstract were imported from PubMed on 30 Aug 2026.

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