Regional variation and healthcare utilization patterns in Medication-related osteonecrosis of the jaw: A nationwide cohort study in Korea.

Authors

Jin-Sil Hong, Keun-Suh Kim, Jung-Hyun Park, Sung Hye Kong, Tae-Jin Song, Kwang-Hyun Lim, Jin-Woo Kim, Hyo-Jung Lee

Published in

Cranio : the journal of craniomandibular practice. Pages 1-9. Aug 30, 2026. Epub Aug 30, 2026.

Abstract

Medication-related osteonecrosis of the jaw (MRONJ) is a serious complication associated with antiresorptive and antiangiogenic agents. This study evaluated regional differences in MRONJ diagnosis and surgical management in Korea.
Using the National Health Insurance Service-Health Screening Cohort, individuals aged ≥50 years between 2010 and 2019 were analyzed. MRONJ cases were identified using KCD-7 diagnosis and procedure codes.
A total of 4,493 MRONJ diagnoses and 1,671 surgical treatments were identified. Diagnoses and surgeries were most frequent in Gyeonggi-do, Seoul, and Gyeongsangbuk-do, whereas relative burden was higher in several non-metropolitan regions. Care was concentrated in tertiary general hospitals and dental hospitals. Region-out diagnosis and surgery rates were highest in Gyeonggi-do (40.8% and 28.4%, respectively), with significant regional differences in healthcare utilization (p < .001). .
Regional disparities exist in MRONJ diagnosis and surgical management in Korea, suggesting imbalances in healthcare resources, specialized care access, and referral patterns.

PMID:
42669059
Bibliographic data and abstract were imported from PubMed on 30 Aug 2026.

Read full publication at:
Please sign in to see all details.

Stats

1-terrible, 9-excellent. How would you rate this publication? Sign in in to submit your rating.

Post a comment

You need to be signed in to post comments. You can sign in here.

Comments

There are no comments yet.