Anticandidal Efficacy of a Paste Containing Capric Acid and a Lysozyme-Chitosan Oligosaccharide Conjugate.

Authors

Mayu Miyanohara, Hidenori Yamada, Takako Nakatsuka, Masaaki Okamoto, Nobuhiro Hanada, Hiroki Kageshima, Shouichirou Hirano, Takatoshi Murata

Published in

Medical mycology journal. Volume 67. Issue 3. Pages 207-211.

Abstract

We report a case series evaluating a novel oral care paste containing capric acid and a lysozyme-chitosan oligosaccharide conjugate (LYZOX). Ten patients with asymptomatic oral Candida colonization performed twice-daily self-care. Clinical eradication was achieved in 80% of cases, including polymicrobial infections involving Candida albicans, Candida glabrata, and Candida parapsilosis. This non-pharmacological approach effectively eliminated Candida species without adverse effects, suggesting a safe, daily preventive strategy for asymptomatic carriers in the maintenance phase of dental treatment.

PMID:
42669483
Bibliographic data and abstract were imported from PubMed on 31 Aug 2026.

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