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Intraocular carcinosarcoma with osteosarcomatous component arising from iridociliary adenocarcinoma in a dog.

Created on 31 Aug 2026

Authors

Miyuu Kakimoto, Kotoko Fukuyo, Chisa Miura, Yuto Sano

Published in

The Journal of veterinary medical science. Aug 28, 2026. Epub Aug 28, 2026.

Abstract

A 9-year-old neutered male Labrador Retriever presented with increased intraocular pressure in the left eye and underwent enucleation for a suspected intraocular tumor. Grossly, a white to greyish-white solid mass occupied the anterior segment and was partially contiguous with the lens. Histologically, the tumor exhibited biphasic proliferation of epithelial and mesenchymal components. The mesenchymal component showed osteoid formation, and transitional features were observed between the two components. Based on histological and immunohistochemical findings, the tumor was diagnosed as a carcinosarcoma composed of an iridociliary adenocarcinoma component and an osteosarcomatous component. This is the first report of carcinosarcoma in the canine eye, expanding the understanding of the morphological diversity and histogenetic characteristics of canine iridociliary tumors.

PMID:
42669475
Bibliographic data and abstract were imported from PubMed on 31 Aug 2026.

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