Daridorexant- Case Report of Possible Side-Effect in Rare Mitochondrial Disorder.

Authors

Sven Svedmyr, Joel Bergqvist

Published in

Journal of sleep research. Pages e70440. Aug 31, 2026. Epub Aug 31, 2026.

Abstract

This case report describes a 40-year-old woman with maternally inherited diabetes and deafness (MIDD), a rare mitochondrial disorder, who received treatment with daridorexant due to severe chronic insomnia. She developed progression of her MIDD symptoms during treatment. Caution is warranted when initiating daridorexant treatment in patients with mitochondrial disorders.

PMID:
42674807
Bibliographic data and abstract were imported from PubMed on 01 Sep 2026.

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