Which Factors Influence Local Recurrence After Oncological Ablation of Midfacial Tumors?

Authors

Yao Yu, Qian Sun, Wen-Bo Zhang, Xin Peng

Published in

The Journal of craniofacial surgery. Sep 01, 2026. Epub Sep 01, 2026.

Abstract

The purpose of this study is to evaluate the incidence of locally recurrent midfacial tumors and the associated clinical features and risk factors.
This is a retrospective cohort study. Records of 327 midfacial tumor patients treated between 2010 and 2018 were reviewed. Clinical features and directions associated with local recurrence were analyzed.
The study sample was composed of 327 subjects, and had a male-to-female ratio of 1.24:1. The median age was 57 years (range, 13-84 y). The median follow-up time was 28 months (range, 8-160 mo). The local recurrence rate for midfacial tumors was 32.8%, and was highest for sarcomas (55.9%), followed by ACCs (45.9%), SCCs (19.3%), and ameloblastomas (10.3%). The most frequent sites of recurrence were the superior aspect. SCC recurrence was associated with tumor size, cervical metastasis, and postoperative radiotherapy. ACC recurrence was associated with tumor size, primary site, and positive first margin. Ameloblastoma recurrence was associated with conservative surgery.
Most frequent sites of local recurrence in midfacial neoplasms were the superior aspect. Midfacial tumor recurrence was associated with pathology, tumor size, primary site, positive margin, surgical method, or postoperative radiotherapy.
Level III-Retrospective comparative study.

PMID:
42676212
Bibliographic data and abstract were imported from PubMed on 01 Sep 2026.

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