LED red light therapy for relief of primary dysmenorrhea: An open, single-group target value clinical trial.

Authors

Bin Yi, Dandan Wang, Ling Wei, Jun He, Qian Yu, Lei Wu, Yilin Wang, Yajuan Wang, Nan Song, Li Guo

Published in

PloS one. Volume 21. Issue 9. Pages e0356618. Epub Sep 01, 2026.

Abstract

To evaluate the efficacy and safety of LED red light therapy in alleviating primary dysmenorrhea.
A total of 119 patients with primary dysmenorrhea were enrolled in 2022. The intervention was LED red light therapy administered 7 days before menstruation. Clinical outcomes were assessed after three menstrual cycles.
After three cycles of treatment, the mean reduction rate in the Visual Analog Scale (VAS) score was 63.62%. The overall effective rate of the device was 98.32%. The total score of the COX Menstrual Symptom Scale decreased by 72.93%, with specific reductions of 72.55% in symptom severity and 73.26% in pain duration. No severe adverse events were reported during the trial. Only one adverse event (0.84%) was considered device-related.
LED red light therapy is safe and effective for the treatment of primary dysmenorrhea.
ChiCTR2600116460.

PMID:
42678980
Bibliographic data and abstract were imported from PubMed on 02 Sep 2026.

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