[Calibrated respiratory inductance plethysmography in the evaluation of respiratory mechanics and diagnosis of obstructive sleep apnea-hypopnea syndrome in female patients].

Authors

Jincheng Hou, Xiaole Lu, Ning Su

Published in

Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery. Volume 40. Issue 9. Pages 822-827.

Abstract

Objective:To investigate the respiratory mechanics characteristics of female patients with obstructive sleep apnea-hypopnea syndrome（OSAHS） using calibrated respiratory inductance plethysmography（cRIP）, and to evaluate the clinical value of the Thoraco-Abdominal Asynchrony Index（TAAI） in identifying subclinical respiratory effort in women. Methods:A retrospective case-control study was conducted. Forty female OSAHS patients（female group） treated in the Department of Otorhinolaryngology at Liaoning Provincial People's Hospital from January 2022 to October 2025 were included. Through propensity score matching（PSM）, 40 male patients matched for age, body mass index（BMI）, and apnea-hypopnea index（AHI） during the same period were selected as the male group. All patients underwent simultaneous polysomnography（PSG） and cRIP monitoring. Differences in the percentage of thoraco-abdominal asynchrony time and TAAI were compared between the two groups. Pearson correlation analysis was used to explore the relationship between TAAI and Hamilton Anxiety Scale（HAMA） scores. Additionally, an independent validation cohort consisting of 30 female patients with upper airway resistance syndrome（UARS） and 30 age-matched healthy female controls was recruited. The diagnostic efficacy of TAAI for upper airway resistance syndrome（UARS） was evaluated using receiver operating characteristic（ROC） curve analysis. Results:With no significant difference in AHI between groups, the full-night microarousal index in the female group（25.6±8.9 events/h） was significantly higher than that in the male group（18.3±7.2 events/h, P<0.001）. cRIP analysis showed that the full-night percentage of thoraco-abdominal asynchrony time in the female group（24.6±8.9）% was significantly higher than that in the male group（17.6±7.1）%, P<0.001. The full-night TAAI in the female group（5.1±3.2） was also significantly higher than that in the male group（3.6±2.9, P<0.001）. Correlation analysis revealed a significant positive correlation between TAAI and HAMA scores in the female group（r=0.636, P<0.001）. ROC curve analysis indicated that the area under the curve（AUC） of TAAI for diagnosing UARS in women was 0.902（95%CI 0.823-0.981）. At a cut-off value of 3.2, the diagnostic sensitivity was 86.7% and specificity was 90.0%. Conclusion:Female OSAHS patients exhibited more significant respiratory effort（Thoraco-Abdominal Paradox） and higher microarousal frequency compared to male patients with similar disease severity. The cRIP-quantified TAAI can effectively identify covert respiratory disturbances characterized by increased upper airway resistance, and this index is closely associated with anxiety levels in female patients. TAAI can serve as a quantitative tool to assist in diagnosing UARS in women, demonstrating considerable clinical application value.

PMID:
42686397
Bibliographic data and abstract were imported from PubMed on 03 Sep 2026.

Read full publication at:
Please sign in to see all details.

Stats

1-terrible, 9-excellent. How would you rate this publication? Sign in in to submit your rating.

Post a comment

You need to be signed in to post comments. You can sign in here.

Comments

There are no comments yet.