Atlantoaxial dislocation in a patient with Neurofibromatosis type 1: Case report and review.

Authors

Abolfazl Rahimizadeh, Housain Soufiani, Khodakaram Rastegar, Abdolhadi Daneshi, Chia Peroutighalat, Mahan Amirzadeh, Naser Asgari

Published in

Surgical neurology international. Volume 17. Pages 444. Epub Aug 07, 2026.

Abstract

Neurofibromatosis type 1 (NF1) or von Recklinghausen's disease is a complex multi-system genetic disorder characterized by neurocutaneous manifestations, nervous system affection, and various skeletal dysplasia. Rarely, this disorder might be associated with atlantoaxial dislocation (AAD).
A 65-year-old male with a prior diagnosis of (NF1) was referred due to progressive spastic quadriparesis. Dynamic cervical spine radiographs and magnetic resonance showed reducible AAD with cervicomedullary cord compression/myelopathy. Triple construct C1-C2 screw-rod-hook fixation results in steady postoperative neurological recovery.
Here, we reviewed the clinical presentation, diagnostic challenges, and surgical fusion for C1-C2 instability in a 65-year-old male with type 1 (NF1) and cervicomedullary cord compression.

PMID:
42694777
Bibliographic data and abstract were imported from PubMed on 04 Sep 2026.

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