Hidradenoma papilliferum of the caruncle: a case report.

Authors

Amer Alemam, Husam Khaleel, Ghadeer Almuhaisen, Ayman Musleh, Hashem Abu Serhan

Published in

Journal of surgical case reports. Volume 2026. Issue 9. Pages rjag789. Epub Sep 03, 2026.

Abstract

Hidradenoma papilliferum (HAP) is a rare benign adnexal tumor of apocrine differentiation, typically occurring in the vulvar or perianal region of women. We report an exceptionally rare case of HAP arising from the lacrimal caruncle, with only one similar case previously documented in the ophthalmic literature. A 61-year-old woman presented with a 3-month history of a painless, vascularized reddish mass over the right caruncle. Complete surgical excision was performed without complications. Histopathological examination revealed a well-circumscribed lesion with papillary and glandular architecture, fibrovascular cores, and a characteristic bilayered epithelium with apocrine features, consistent with HAP and without evidence of malignancy. This case highlights the importance of considering HAP in the differential diagnosis of caruncular tumors and confirms surgical excision as curative.

PMID:
42695006
Bibliographic data and abstract were imported from PubMed on 04 Sep 2026.

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