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The expanding role of Cav3 channels in glioblastoma.

Created on 05 Sep 2026

Authors

Maria Casals, Judit Herreros, Carles Cantí

Published in

Trends in pharmacological sciences. Sep 04, 2026. Epub Sep 04, 2026.

Abstract

Tumor-intrinsic voltage-gated Cav3 calcium channels, comprising the Cav3.1, Cav3.2 and Cav3.3 isoforms, have been implicated in cancer cell proliferation and survival. Recent work by Dube et al. reveals a role for microenvironmental Cav3.2 channels in glioblastoma, promoting neuron-cancer cell crosstalk and identifying changes in immune-related programs associated with Cav3.2 deficiency.

PMID:
42697770
Bibliographic data and abstract were imported from PubMed on 05 Sep 2026.

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