Why pharmacological concepts survive despite scientific progress.

Authors

Pierre-Louis Toutain, Peggy Gandia, Didier Concordet

Published in

Trends in pharmacological sciences. Sep 05, 2026. Epub Sep 05, 2026.

Abstract

Scientific disciplines routinely reassess methods but rarely the concepts guiding scientific reasoning. We identify three mechanisms of conceptual persistence: amnesia, institutionalisation, and reification-the process by which an operational construct is regarded as biological reality. These mechanisms may impede scientific self-correction, a challenge increasingly relevant as artificial intelligence learns from scientific literature.

PMID:
42697769
Bibliographic data and abstract were imported from PubMed on 05 Sep 2026.

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