Authors
Idoia Morilla, Edinson Caviedes, Regina Gironés Sarrió, Borja López de San Vicente Hernández, Natalia Luque Caro, Sonia Del Barco, Juana M Cano, María Ángeles Vaz-Salgado
Published in
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico. Sep 04, 2026. Epub Sep 04, 2026.
Abstract
Glioblastoma is the most aggressive and common malignant primary brain tumor among adults. Due to its aggressiveness, GBM entails a short median overall survival and fatal outcomes. Incidence notably increases with age, 50% of patients being diagnosed at the age of 65 or older. Given that cognitive loss is commonly confused with age-related cognitive impairment, delays in diagnosis are frequent. Furthermore, the elderly are a vulnerable group, commonly having poorer functional status, more comorbidities, and reduced tolerance to intensive treatments. Therefore, clinical and therapeutic implications should be considered within a multidisciplinary approach. The aim of the present study was to review the current knowledge on the management of glioblastoma in the elderly population (≥ 65 years).
PMID:
42698043
Bibliographic data and abstract were imported from PubMed on 05 Sep 2026.
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