C - reactive protein to albumin ratio as predictor of severity and outcome in acute pancreatitis.

Authors

Umesh Pratap Singh, Manzar Hussain Usmani, Mukund Pandey, Pooja Patel

Published in

Bioinformation. Volume 22. Issue 6. Pages 3521-3526. Epub Jun 30, 2026.

Abstract

Early and accurate prediction of severity in acute pancreatitis remains a major clinical challenge, particularly in resource-limited settings. Hence, this cross-sectional study evaluated 100 patients to assess the prognostic value of the CRP/Albumin ratio (CAR) in comparison with BISAP and other parameters. Disease severity was mild in 40%, moderate in 30% and severe in 30%, with ICU admission in 23% and overall mortality of 5%, increasing with severity. Non-survivors had significantly higher age (62.6 ± 7.09 vs 40.41 ± 13.66 years), urea (78.72 ± 66.08 vs 24.09 ± 13.99 mg/dL), creatinine (2.69 ± 1.68 vs 0.84 ± 0.43 mg/dL), CRP (182.61 ± 141.55 vs 75.98 ± 82.76 mg/L), CAR (107.18 ± 106.30 vs 28.09 ± 38.10) and BISAP scores (4.6 ± 0.55 vs 0.85 ± 0.99), along with lower albumin levels (2.11 ± 0.87 vs 3.20 ± 0.98 g/dL). Thus, BISAP showed the highest predictive accuracy (AUC = 1.000), followed by creatinine (0.985), age (0.952) and CAR (0.930).

PMID:
42701770
Bibliographic data and abstract were imported from PubMed on 06 Sep 2026.

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