[Chronic hyponatremia secondary to drug-induced syndrome of inappropriate antidiuretic hormone secretion - The role of oral urea as a safe and effective therapeutic alternative].

Authors

María Jiménez Aceituno, Ana Segarra Balao, Juan de Dios Barranco Ochoa

Published in

Nutricion hospitalaria. Sep 01, 2026. Epub Sep 01, 2026.

Abstract

hyponatremia is one of the most common electrolyte disturbances in clinical practice. Among the causes of euvolemic hyponatremia, syndrome of inappropriate antidiuretic hormone secretion (SIADH) is one of the most prevalent etiologies, with medications being one of its common triggers.
we present the case of a 71-year-old woman with chronic euvolemic hyponatremia secondary to drug-induced SIADH, in the context of ongoing treatment with multiple potentially implicated medications.
the significance of this case lies in demonstrating the efficacy and safety of oral urea as a maintenance treatment in a patient for whom discontinuation of the causative medications was not possible due to the need for chronic psychopharmacological treatment. It also illustrates the profile of a patient who is a candidate for treatment with oral urea: chronic euvolemic hyponatremia secondary to SIADH, in which fluid restriction is not feasible, and other therapeutic alternatives presented limitations.

PMID:
42703990
Bibliographic data and abstract were imported from PubMed on 07 Sep 2026.

Read full publication at:
Please sign in to see all details.

Stats

1-terrible, 9-excellent. How would you rate this publication? Sign in in to submit your rating.

Post a comment

You need to be signed in to post comments. You can sign in here.

Comments

There are no comments yet.