Authors
Andrea Ulloa-Fernández, Marica Markovic, Julia Fernández-Pérez, Georg Stary, Aleksandr Ovsianikov
Published in
Advanced healthcare materials. Volume 15. Issue 9. Pages e03806. Epub Nov 27, 2025.
Abstract
Chronic, non-communicable inflammatory skin diseases, are a group of inflammatory conditions with high prevalence across the world and represent a significant challenge in medicine, due to the high number of patients arriving for medical consultations. The development of engineered skin tissue models aims to create advanced in vitro models that accurately recapitulate various skin disorders. Furthermore, the introduction of the 3Rs framework to reduce animal testing, alongside specific legislation intended to minimize such testing, has driven research toward developing in vitro models that closely imitate human conditions and skin pathologies, while also being suitable for testing new therapeutic and cosmetic products. In this context, advancements in bioprinting technologies, which promise to ensure consistent quality, reduce technical variances, and enable upscaling, can improve the reproducibility and performance of such models. This work discusses current advancements in the field of bioprinting of in vitro skin models with a particular focus on their application in the research of immune-mediated diseases.
PMID:
41307229
Bibliographic data and abstract were imported from PubMed on 08 Sep 2026.
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