[Advances in imaging techniques of the distal aqueous outflow pathway in glaucoma].

Authors

G H Ai, Y F Cai, X Tan, K L Qiu, H X Wang

Published in

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology. Volume 62. Issue 9. Pages 737-744. Sep 11, 2026.

Abstract

The distal aqueous humor outflow pathway is an essential component of aqueous humor drainage and is closely associated with intraocular pressure control after minimally invasive glaucoma surgery (MIGS). However, in vivo assessment of its structure and function remains a major clinical challenge. Optical coherence tomography enables continuous visualization of the distal outflow pathway beyond Schlemm's canal through improved micrometer-scale axial resolution, although its performance is limited by tissue overlap and similar optical signals. Aqueous angiography visualizes segmental aqueous humor outflow intraoperatively and assesses distal outflow patency. Hemoglobin video imaging exploits the differential optical absorption of hemoglobin and aqueous humor to enable dynamic, quantitative evaluation of aqueous humor outflow. This review summarizes recent advances in imaging of the distal aqueous humor outflow pathway and discusses their potential applications in evaluating MIGS outcomes and guiding individualized treatment.

PMID:
42706146
Bibliographic data and abstract were imported from PubMed on 08 Sep 2026.

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