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Balancing Thrombosis and Bleeding: A Case Report of Acute Myocardial Infarction in an Elderly Patient With Hemophilia A.

Created on 08 Sep 2026

Authors

Dehua Huang, Xi Yang, Xianglan Zhang, Xiaoyu Huang

Published in

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions. Sep 07, 2026. Epub Sep 07, 2026.

Abstract

Hemophilia A combined with acute myocardial infarction (AMI) is rare and challenging to treat. This article reports a 65-year-old patient with hemophilia A admitted for acute inferior ST-segment elevation myocardial infarction, who successfully underwent emergency drug-coated balloon (DCB) angioplasty with factor VIII replacement support. Dual antiplatelet therapy (DAPT) was discontinued 3 weeks after the operation, after which the patient received neither antithrombotic therapy nor replacement therapy, while comprehensive risk factor control was intensified. No recurrent thrombotic or hemorrhagic events were observed during the 1-year follow-up. This case suggests that the DCB strategy can shorten the required duration of antithrombotic treatment, and discontinuing antithrombotic and replacement therapies may be safe for selected patients, with comprehensive risk factor control serving as the core antithrombotic intervention at this stage.

PMID:
42706764
Bibliographic data and abstract were imported from PubMed on 08 Sep 2026.

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