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Effectiveness of Resistance Training in People With Down Syndrome: Systematic Review and Meta-Analysis.

Created on 08 Sep 2026

Authors

María Jesús Benzo Iglesias, Lucía Torres Álamo, Alejandro Salazar, Patricia Rocamora Pérez, David Manuel Lucena Antón

Published in

Journal of applied research in intellectual disabilities : JARID. Volume 39. Issue 5. Pages e70302.

Abstract

We aimed to evaluate the effectiveness of resistance training (RT) in people with Down syndrome (DS) as a way of improving strength, physical and metabolic function, and possible adverse effects.
Systematic review and meta-analysis of RCTs in PubMed, PEDro, Scopus, and WoS databases in September-2023, registered in PROSPERO (CRD42022312810). Methodological quality and risk of bias were analysed using the PEDro scale, the Downs & Black Checklist, and the Cochrane Collaboration Risk of Bias Tool.
Sixteen articles were included. RT increased the strength (SMD = 1.88; 95% CI = (1.26; 2.51); I2 = 72%) and improved physical function (SMD = -0.58; 95% CI = (-1.06; -0.11); I2 = 13%), but there were no clear results on whether it improved anthropometric and cardiorespiratory measures. There were no serious adverse effects.
An increase in overall and maximal muscle strength and improved physical function was produced by RT in DS people. RT is a safe technique as serious adverse effects were not produced.

PMID:
42708805
Bibliographic data and abstract were imported from PubMed on 08 Sep 2026.

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