Historical perspective on evolution of neuraxial delivery for pain (1975-2025).

Authors

Tony Yaksh, Salim Michel Hayek

Published in

Regional anesthesia and pain medicine. Volume 51. Issue 9. Pages 1012-1027. Sep 08, 2026. Epub Sep 08, 2026.

Abstract

In the present commentary, we consider the historical trajectory that reflects the evolution of neuraxial therapeutics that has transpired over the last 50 or so years, with a particular emphasis on its application to pain and its management. The review addresses the advances that led to where we are now in the 21st century with neuraxially targeted therapeutics and consideration of where this thread leads.

PMID:
42710949
Bibliographic data and abstract were imported from PubMed on 09 Sep 2026.

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