Dietary macronutrient intake and the gut microbiome in adults undergoing bariatric surgery.

Authors

Sarah J Lande, Lydia M Stephney, Lucia A Gonzalez Ramirez, Paula-Dene C Nesbeth, Terryl J Hartman, Dean P Jones, Damaskini Valvi, Elizabeth M Hechenbleikner, Edward Lin, Rob S McConnell, Vaia Lida Chatzi, Jessica A Alvarez, Thomas R Ziegler

Published in

European journal of clinical nutrition. Sep 08, 2026. Epub Sep 08, 2026.

Abstract

Information linking diet with the gut microbiome in bariatric surgery is limited. This pilot study examined correlations between macronutrient intake and gut microbiome indexes in adults undergoing bariatric surgery. Participants were 29 adults (93% female) undergoing bariatric surgery. Food records were used to estimate daily macronutrient intake. Shotgun sequencing was used in pre- and post-operative stool samples to identify changes in microbial composition. Diversity indices and differential abundance were calculated, and correlations between dietary intake and outcomes were assessed using linear regression and machine learning models. Phyla and genera were statistically correlated with macronutrient intakes, in particular, intake of soluble fiber, insoluble fiber, and dietary glycemic index. Changes in nutrient-related functional gene pathways were linked to change in HEI-2015 scores and in soluble and insoluble fiber intake following bariatric surgery. In this hypothesis-generating study, intakes of specific macronutrients were correlated with several microbial phyla, genera, and nutrient-related functional gene pathways.

PMID:
42711397
Bibliographic data and abstract were imported from PubMed on 09 Sep 2026.

Read full publication at:
Please sign in to see all details.

Stats

1-terrible, 9-excellent. How would you rate this publication? Sign in in to submit your rating.

Post a comment

You need to be signed in to post comments. You can sign in here.

Comments

There are no comments yet.