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Minimally invasive organ-preserving surgery for rectal gastrointestinal stromal tumour: Report of two cases with long-term follow-up.

Created on 09 Sep 2026

Authors

Venu Madhav Jarapala, Hemanga Kumar Bhattacharjee, Washim Firoz Khan, Sagar Rathod Rathlavath, Ashmita Jain, Rajendra Kumar Behera, Rajinder Parshad

Published in

Journal of minimal access surgery. Sep 03, 2026. Epub Sep 03, 2026.

Abstract

Rectal gastrointestinal stromal tumours (GISTs) are uncommon and pose technical challenges due to their deep pelvic location and proximity to the anal sphincter complex. Radical resections, although traditionally preferred, often result in significant morbidity. We describe two cases of rectal GIST successfully managed by transanal minimally invasive surgery (TAMIS). One patient received neoadjuvant imatinib to downsize the tumour before excision. Full-thickness transanal tumour excision was achieved without rupture in both cases, with primary rectal wall closure. At 5 and 4 years of follow-up, respectively, both patients remain recurrence-free with full continence. TAMIS represents a safe, oncologically sound, organ-preserving approach for selected rectal GISTs.

PMID:
42714198
Bibliographic data and abstract were imported from PubMed on 09 Sep 2026.

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