Authors
Essa Ceesay, Juval Avala Ntsigouaye, Justina Ucheojor Onwuka, Yang Shanshan, Itunu Olufunke Sokale, Radheshyam Gupta, Marvellous Okeke, Evissi-Kouva Okiemy, Kebba S Bojang, Laurent Belec
Published in
Open forum infectious diseases. Volume 13. Issue 9. Pages ofag509. Epub Sep 09, 2026.
Abstract
Women with HIV face a higher risk of cervical cancer. This review synthesizes evidence on precancerous cervical lesions among women with HIV in sub-Saharan Africa (SSA), regional differences, risk factors, and approaches to integrating cervical cancer prevention into HIV services.
We conducted a comprehensive literature search across PubMed, Embase, Scopus, and Web of Science databases through December 2025 and identified studies evaluating the prevalence of precancerous cervical lesions among women with HIV in SSA. It highlights prevalence, ongoing global efforts, and integration strategies specific to SSA.
The prevalence of precancerous cervical lesions among women with HIV in SSA is higher in Tanzania (71.8%), and Kenya (42%), eastern countries than from western (Nigeria, 26.6%) or southern countries (South Africa, 23.2%), influenced by the distribution of human papillomavirus (HPV) genotypes, including higher-risk HPV (HR-HPV) such as HPV 35, which is not targeted by the HPV vaccine.
Given the increased risk among women with HIV and the substantial burden in SSA, evidence suggests that integrating HPV-based cervical cancer screening and vaccination into HIV care platforms could help close the prevention gap and reduce the dual burden among women with HIV in SSA.
PMID:
42719686
Bibliographic data and abstract were imported from PubMed on 10 Sep 2026.
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