Authors
Wanli Liu, Xuanlin Peng, Mengyu He, Hu Chen
Published in
ACS applied materials & interfaces. Sep 10, 2026. Epub Sep 10, 2026.
Abstract
Organic electrochemical transistors (OECTs) have emerged as highly promising platforms for next-generation bioelectronic interfaces, fundamentally driven by their unique mixed ionic-electronic conduction and volumetric doping mechanisms. Despite significant progress in understanding electronic transport, the intricate dynamics of ion transport-encompassing interfacial double-layer kinetics and complex electrolyte-channel interactions-continue to constrain ultimate device performance and introduce profound physical complexities. To address this critical gap, this review provides a systematic overview of the regulatory roles of ionic species in OECTs, bridging microscopic ion dynamics with macroscopic device performance. First, the theoretical foundations of ion transport kinetics and interfacial processes are discussed. Next, comprehensive molecular and architectural engineering strategies for optimizing ion transport, including polymer backbone modulation, side-chain tailoring, and the integration of functional electrolyte systems, are systematically examined. This is followed by an exploration of the practical manifestations of these precisely managed ionic effects in advanced applications, specifically highlighting broad biosensing capabilities and biomimetic neuromorphic computing. Finally, the review concludes by identifying persistent challenges, notably the intrinsic trade-off between crystallinity and ionic permeability, and outlines potential future trajectories for the development of robust, high-performance ion-regulated organic bioelectronics.
PMID:
42720985
Bibliographic data and abstract were imported from PubMed on 11 Sep 2026.
Read full publication at:
Please sign in
to see all details.
Advertisement
Stats
- Recommendations n/a n/a positive of 0 vote(s)
- Views 14
- Comments 0