Generalized myasthenia gravis: Clinical trials to watch.

Authors

Sarah Hoffmann, Paolo Doksani, James F Howard

Published in

Med (New York, N.Y.). Volume 7. Issue 9. Pages 101270. Sep 11, 2026.

Abstract

Generalized myasthenia gravis is undergoing a highly dynamic phase of therapeutic development, with ongoing trials increasingly targeting upstream immune mechanisms. This Trial Watch highlights six studies evaluating B cell survival modulation, lymphocyte-directed immune reconstitution, BCMA- and CD19-directed CAR-T cell therapy, T cell engagement, and response-guided combination therapy, and considers their implications for future treatment strategies.

PMID:
42727567
Bibliographic data and abstract were imported from PubMed on 12 Sep 2026.

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