Porcine Skin-Derived Silver Nanoparticles: A Novel Green Synthesis Approach and Molecular Characterization of Their Antimicrobial Potential.

Authors

Kyoung Ran Kim, Bummo Koo, Min Woo Lee, Hyeong-Dong Kim, Jong Ryeul Sohn, Suhng Wook Kim

Published in

International journal of molecular sciences. Volume 27. Issue 8. Apr 15, 2026. Epub Apr 15, 2026.

Abstract

Silver nanoparticles (AgNPs) are widely recognized for their potent antibacterial properties and diverse biomedical applications. While conventional synthesis methods typically rely on chemical-reducing agents that may pose risks to human health and the environment, this study proposes an eco-friendly green synthesis approach utilizing porcine skin extracts. The extracts were prepared through thermal treatment and filtration to serve as a biological reducing agent. Successful synthesis was validated using dynamic light scattering, Fourier transform infrared (FTIR) spectroscopy, UV-Vis spectroscopy, and scanning electron microscopy (SEM). Furthermore, the antimicrobial efficacy of the synthesized AgNPs was evaluated against multidrug-resistant microorganisms, demonstrating significant growth inhibition across various antibiotic-resistant strains. These findings suggest that porcine skin-a readily available bioresource-is a promising precursor for the sustainable production of AgNPs with broad-spectrum antimicrobial potential.

PMID:
42074163
Bibliographic data and abstract were imported from PubMed on 13 Sep 2026.

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