Periodontal health and disease: The contribution of genetics.

Authors

Luciana Macchion Shaddox, Lorri Ann Morford, Luigi Nibali

Published in

Periodontology 2000. Volume 85. Issue 1. Pages 161-181. Epub Nov 23, 2020.

Abstract

Periodontitis is an infectious, inflammatory disease that is associated with a complex interplay between specific bacteria, host response, and environmental factors. Because of its high degree of familial aggregation, specifically for the more aggressive forms of the disease, genetics factors have been implicated in disease pathogenesis for several decades. This review provides an overview of what we currently know regarding the genetic and epigenetic contributions to periodontal disease and discusses future opportunities in the field.

PMID:
33226705
Bibliographic data and abstract were imported from PubMed on 13 Sep 2026.

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